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, Rouel, J. P. , Chouinard, P. , Greenwood, S. , Andreoli, M. M. , and Brenna, J. , and Bergeron, N. , Yamasaki, M. E. , Djalali, M. Effect of conjugated linoleic acid isomers on growth factor-induced proliferation of human breast cancer cells. Punicic acid from Trichosanthes kirilowii seed oil is rapidly metabolized to conjugated linoleic acid in rats. A. View abstract. M. Changhua, L. A. Rigano, L. T. , Jeung, E. Conjugated linoleic acid-enriched butter fat alters mammary gland morphogenesis and reduces cancer risk in rats. , Shingfield, K. , and Romagnolo, D. Xu, X. Brown, J. , Mazzette, R. H. Bharathan, M. , Steinberg, H. Induction of apoptosis and inhibition of NF-kappaB activation in human prostate cancer cells by the cis-9, trans-11 but not the trans-10, cis-12 isomer of conjugated linoleic acid. E. , and Chlubek, D. K. , Conway, J. , Zimmer, A. , Wannemuehler, M. Shingfield, K. , Shingfield, K. Zambell, K. , and Zervas, G. , Mouloungui, Z. D. Effect of dietary starch or micro algae supplementation on rumen fermentation and milk fatty acid composition of dairy cows. E. Dietary conjugated linoleic acid in the cis-9, trans-11 isoform reduces parathyroid hormone in male, but not female, rats. Diabetes. Exploring polymorphisms and effects of candidate genes on milk fat quality in dairy sheep. View abstract. Risks and benefits of nutritional supplements during pregnancy. Physical Properties of Two Isomers of Conjugated Linoleic Acid. S. , Dal Maso, M. View abstract. , Pastorelli, G. P. , and Domeneghini, C. C. Smedman, A. View abstract. Torres, C. J. , and Sok, D. , Galibois, I. Bioconversion of vaccenic acid to conjugated linoleic acid in humans. I. , and Stanton, C. , Heck, J. Losses from the gastrointestinal can occur because of symptoms such as vomiting or diarrhea, as well as fistulae and stomas. , Scalerandi, M. View abstract. Conjugated linoleic acid increases in milk from cows fed condensed corn distillers solubles and fish oil. , and Miglietta, A. , Let, M. View abstract. View abstract. A. Dietary oxidized fat prevents ethanol-induced triacylglycerol accumulation and increases expression of PPARalpha target genes in rat liver. P. J. View abstract. Sikorski, A. View abstract. , Lavillonniere, F. P. , Baumgard, L. , and Yamada, K. T. Weight loss occurs when the body is expending more energy in work and metabolism than it is absorbing from food or other nutrients. , Goonewardene, L. , and Farina, F. Trans-vaccenic acid is desaturated to conjugated linoleic acid in mice. , and Fernandes, G. , and McAllister, T. J. View abstract. View abstract. Aryaeian, N. , Shinohara, K. , Rybicka, M. Mining the microbiota of the neonatal gastrointestinal tract for conjugated linoleic acid-producing bifidobacteria. , Koh, I. , Borel, I. , Eastridge, M. , Murphy, B. , and Bauman, D. A. Polyunsaturated fatty acids and conjugated linoleic acid isomers in breast milk are associated with plasma non-esterified and erythrocyte membrane fatty acid composition in lactating women. , and Pariza, M. , Szakacs, G. , and Nelson, G. View clinical references for this vitamin or supplement. Terpstra, A. Conjugated linoleic acid modulates tissue levels of chemical mediators and immunoglobulins in rats. B. A. , and Jahreis, G. , Valentini, A. , Gale, B. R. , Toivonen, V. H. Rosberg-Cody, E. , and Wallace, R. , and Trugo, N. DeLany, J. , Gonzalvez, A. The effect of conjugated linoleic acid on platelet function, platelet fatty acid composition, and blood coagulation in humans. , Ujino, Y. , and Rastrelli, F. C. View abstract. Cell nanomechanics and focal adhesions are regulated by retinol and conjugated linoleic acid in a dose-dependent manner. Fatty acids and epithelial permeability: effect of conjugated linoleic acid in Caco-2 cells. , and Wallace, R. Effects of low-protein diets and rumen-protected conjugated linoleic acid on production and carcass traits of growing double-muscled Piemontese bulls. Inverse association between dietary and serum conjugated linoleic acid and risk of breast cancer in postmenopausal women. Bissonauth, V. , Suzuki, H. , Banu, J. View abstract. , Piccioni, E. Association between dietary conjugated linoleic acid and bone mineral density in postmenopausal women. S. , Lamb, G. Total lipids of Sarda sheep meat that include the fatty acid and alkenyl composition and the CLA and trans-18:1 isomers. , Meneses, F. Isomers of conjugated linoleic acids are synthesized via different mechanisms in ruminal digesta and bacteria. Chen, B. , Park, H. Conjugated linoleic acid supplementation reduces adipose tissue by apoptosis and develops lipodystrophy in mice. An oil mixture with trans-10, cis-12 conjugated linoleic acid increases markers of inflammation and in vivo lipid peroxidation compared with cis-9, trans-11 conjugated linoleic acid in postmenopausal women. , and Gibney, M. , Mansho, K. Dietary conjugated linoleic acid reduces body fat mass and affects gene expression of proteins regulating energy metabolism in mice. , Miller, A. Conjugated linoleic acid supplementation in humans: effects on body composition and energy expenditure. M. Riserus, U. W. View abstract. View abstract. , Roach, J. , Iwata, T. Cyclooxygenase-2 promoter activation by the aromatic hydrocarbon receptor in breast cancer mcf-7 cells: repressive effects of conjugated linoleic acid. J. V. , and Larson, S. M. View abstract. Short-term fatty acid intervention elicits differential gene expression responses in adipose tissue from lean and overweight men. , Palmquist, D. Rennet paste from lambs fed a milk substitute supplemented with Lactobacillus acidophilus: effects on lipolysis in ovine cheese. , Kim, L. View abstract. , Machalinski, B. , Kishihara, K. , and Ezaki, O. View abstract. M. , Ferrari, P. Y. , Hardin, J. Taking conjugated linoleic acid for 12 weeks seems to improve well-being in people with birch allergies. The effect of conjugated linoleic acid on the viability and metabolism of human osteoblast-like cells. J. , Arnlov, J. M. , Turpeinen, A. , and Ip, C. E. , McGee, S. A. A. , Roche, H. W. , Santos, J. Dietary conjugated linoleic acid affects morphofunctional and chemical aspects of subcutaneous adipose tissue in heavy pigs. , and Lee, K. , Pico, C. View abstract. , Gonzalez, M. View abstract. , Albenzio, M. , and Leaf, A. Probiotic in lamb rennet paste enhances rennet lipolytic activity, and conjugated linoleic acid and linoleic acid content in Pecorino cheese. P. Takahashi, Y. , Cozzi, G. , Scalerandi, M. Choi, Y. , and Kasai, M. , Arnlov, J. Genetic variability of fatty acids in bovine milk. , Liu, J. Metabolism of linoleic acid by human gut bacteria: different routes for biosynthesis of conjugated linoleic acid. , Murphy, J. See what your medical symptoms could mean, and learn about possible conditions. , Barron, L. View abstract. M. J. Some research shows that taking conjugated linoleic acid, alone or along with creatine and whey protein, helps increase strength and improve lean tissue mass in people who are strength training. Conjugated linoleic acid modulation of cell membrane in leukemia cells. , and Campos, H. , Sun, C. , Mossoba, M. Bretillon, L. , Nelson, G. P. , Ma, X. G. J. , Nonaka, M. Shen, X. J. Ringseis, R. View abstract. M. Weight loss issues related to specific diseases include. Song, D. , Machalinski, B. , Oh, M. , and Mammi, S. Metabolic fate of fatty acids involved in ruminal biohydrogenation in sheep fed concentrate or herbage with or without tannins. , Suganuma, T. , Wang, Q. , and Gibson, M. , and Griinari, J. , and Hendriks, H. , Safdar, A. Yang, Y. , Machalinski, B. T. , Oji, M. Early research suggest that taking conjugated linoleic acid, alone or along with vitamin E, reduces pain and morning stiffness, as well as lab markers of swelling, compared to pretreatment in people with rheumatoid arthritis. Relation between the intake of milk fat and the occurrence of conjugated linoleic acid in human adipose tissue. A. , and Mintzer, E. , Tsujita, A. N. , Koyanagi, N. S. , Wang, H. , Gammazza, A. View abstract. L. T. Banu, J. , and Kinlaw, W. , Lankhorst, A. , Chardigny, J. , Aboud, A. F. , Lee, Y. R. P. P. View abstract. Drinking milk containing conjugated linoleic acid does not seem to improve levels of cholesterol or blood fats called triglycerides in people with mildly high cholesterol levels. View abstract. Toomey, S. , Collomb, M. , Lawrence, P. , and Heidari, M. Regulation of stearoyl-CoA desaturase activity by the trans-10,cis-12 isomer of conjugated linoleic acid in HepG2 cells. Tsuboyama-Kasaoka, N. , and Zhao, D. , Barrett, E. Modulation peroxisome proliferators activated receptor alpha (PPAR alpha) and acyl coenzyme A: cholesterol acyltransferase1 (ACAT1) gene expression by fatty acids in foam cell. View abstract. Herbel BK, McGuire MK, McGuire MA, Shultz TD. O. Bispo, E. , Chouinard, P. Visonneau, S. Synthesis and Structural Analysis of Structured Triacylglycerols with CLA Isomers in the sn-2- Position. , Lock, A. , Bowden, G. In children, taking 3 grams of conjugated linoleic acid daily seems to help reduce body fat. View abstract. View abstract. Torres, A. , Butikofer, U. , Taleban, F. Santora, J. , Amiri, Z. Takahashi, Y. M. , Safranow, K. Choy, J. , Blask, D. F. L. Corl, B. M. I. , Van Nespen, T. Stachowska, E. Won, J. M. , and Rhodes, L. Conjugated linoleic acid supplementation in humans: effects on fatty acid and glycerol kinetics. , Karges, K. , Vlaeminck, B. Wu, Z. K. C. , Portillo, M. Toral, P. Su, N. S. , and Portillo, M. , Ross, R. , Lamarche, B. Benchaar, C. L. , Klem, E. , Oikawa, D. View abstract. Dietary factors and growth and metabolism in experimental tumors. View abstract. H. A. , and Etherton, T. J. , Bontempo, V. Weldon, S. S. H. Dietary conjugated linoleic acid reduces adiposity in lean but not obese Zucker rats. , Rouel, J. , Kasai, M. , Cannito, S. Russell, J. Pregnancy and breast-feeding: Conjugated linoleic acid is LIKELY SAFE when taken by mouth in food amounts. Conjugated linoleic acid and human health: a critical evaluation of the evidence. , and Lopez-Sabater, M. A. Hide Names Review this Treatment 70 User Reviews See Brand Products CONJUGATED LINOLEIC ACID Overview Information Conjugated linoleic acid refers to a group of chemicals found in the fatty acid linoleic acid. , Nam, S. , Chew, B. L. , Lee, J. J. View abstract. , Olsen, A. Tissue proximate, fatty acid, vitamin, and cholesterol content. Second Opinion Read expert perspectives on popular health topics. Effects of conjugated linoleic acid isomers on the hepatic microsomal desaturation activities in vitro. Inhibitory effect of conjugated linoleic acid on linoleic acid elongation in transformed yeast with human elongase. Effects of conjugated linoleic acid on body fat and energy metabolism in the mouse. S. , Keim, N. van Dorland, H. , Defa, L. , Adams, D. R. , Mitchell, S. View abstract. View abstract. View abstract. , Yin, J. In theory, conjugated linoleic acid might increase the risk of bruising and bleeding in people with bleeding disorders. D. Conjugated linoleic acid for altering body composition and treating obesity. , Akimoto, Y. , Wang, G. Cheese manufacture with milk with elevated conjugated linoleic acid levels caused by dietary manipulation. View abstract. , Mockel, P. View abstract. View abstract. H. J. , and Nicolaou, A. W. M. M. , Rouel, J. Effectiveness of oils rich in linoleic and linolenic acids to enhance conjugated linoleic acid in milk from dairy cows. , Tahbaz, F. B. , Schone, F. , Yamauchi, K. K. View abstract. , Liu, X. Effects of dietary conjugated linoleic acid in nursery pigs of dirty and clean environments on growth, empty body composition, and immune competence. , Or-Rashid, M. Choi, J. Get Started Resources Second Opinion Read expert perspectives on popular health topics Message Boards Connect with people like you, and get expert guidance on living a healthy life Insurance Guide Get ready for changes to your health care coverage Physician Directory Find a doctor in your area Pain Coach Track your pain levels, triggers, and treatments. , Kushiro, M. Synthesis of structured phospholipids by immobilized phospholipase A2 catalyzed acidolysis. Supplementation with trans10cis12-conjugated linoleic acid induces hyperproinsulinaemia in obese men: close association with impaired insulin sensitivity. , and Doherty, T. , Eberhard, P. , Jung, M. and West, D. Effects of cis-9,trans-11 and trans-10,cis-12 conjugated linoleic acid on immune cell function in healthy humans. , Schmidt, P. Development and characterization of structured lipids containing capric and conjugated linoleic acids as functional dietary lipid molecules. , Wettstein, H. , Bregendahl, K. Shadman, Z. Conjugated linoleic acid supplementation for twelve weeks increases lean body mass in obese humans. , Bailoni, L. , Castellote, A. Turnock, L. Y. View abstract. A. View abstract. E. J. , Benito, P. C. , Serra, A. , and Fievez, V. , Lim, S. Fungal illnesses, endocarditis, many parasitic diseases, AIDS, and some other subacute or occult infections may cause weight loss. View abstract. , and Stanton, C. Bocca, C. Aminot-Gilchrist, D. L. A. , Hosokawa, M. , Hwang, B. J. , Austin, G. View abstract. View abstract. , Candy, L. , Ikeda, A. Choi, Y. M. Get Started My Medicine Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more. , Dwyer, D. C. View abstract. , Di Giancamillo, A. , and Basu, S. , and Yang, C. , Hedayati, M. View abstract. View abstract. Protective action of CLA against oxidative inactivation of paraoxonase 1, an antioxidant enzyme. Conjugated linoleic acid (CLA) inhibits expression of the Spot 14 (THRSP) and fatty acid synthase genes and impairs the growth of human breast cancer and liposarcoma cells. Santercole, V. Colakoglu, S. , Illesca, P. S. , Lee, G. , Dziedziejko, V. A. D. An increase in vitamin A status by the feeding of conjugated linoleic acid. Banni, S. , Lin, J. This can result from conditions that affect the digestive system. , Colombatto, S. , Chardigny, J. , Silvestre, F. , Pronczuk, A. O. , Devery, R. , and Albenzio, M. R. De La Fuente, L. F. View abstract. Dietary fat concentration influences the effects of trans-10, cis-12 conjugated linoleic acid on temporal patterns of energy intake and hypothalamic expression of appetite-controlling genes in mice. View abstract. View abstract. Bu, D. Shultz, T. A. , Capitan, P. Beneficial effects of conjugated linoleic acid and exercise on bone of middle-aged female mice. , Senorans, F. , Park, S. , Horn, W. H. A. , Lemmens, A. , Mignolet, E. Xiao, Y. L. , Bankovic-Calic, N. , Petrosian, M. P. and Anderson, H. Bergamo, P. , and Chilliard, Y. , Francica, S. , Darestani, R. , Iwata, T. H. , and Tanaka, T. M. Differential stimulatory and inhibitory responses of human MCF-7 breast cancer cells to linoleic acid and conjugated linoleic acid in culture. , Yoon Park, J. , and Chlubek, D. , and Ntambi, J. , Bartolini, G. D. M. V. , Devery, R. , Park, Y. Trans-10, cis-12, but not cis-9, trans-11, conjugated linoleic acid attenuates lipogenesis in primary cultures of stromal vascular cells from human adipose tissue. Trans-10, cis-12-conjugated linoleic acid alters hepatic gene expression in a polygenic obese line of mice displaying hepatic lipidosis. F. Cusack, S. , Devitt, A. View abstract. , and McGuire, M. H. Vaccenic acid and cis-9,trans-11 CLA in the rumen and different tissues of pasture- and concentrate-fed beef cattle. D. J. , Xu, C. , Bocher, V. P. , and Palou, A. Turpeinen, A. A. View abstract. Conjugated linoleic acid isomers: differences in metabolism and biological effects. , Chen, X. View abstract. A practical guide to the isolation, analysis and identification of conjugated linoleic acid. 9trans,11trans conjugated linoleic acid inhibits the development of azoxymethane-induced colonic aberrant crypt foci in rats. X. W. View abstract. Christie, W. , Li, D. L. Chemometric deconvolution of gas chromatographic unresolved conjugated linoleic acid isomers triplet in milk samples. P. Stoop, W. , Wang, G. Yamasaki, M. M. Effects of dietary corn oil and vitamin E supplementation on fatty acid profiles and expression of acetyl CoA carboxylase and stearoyl-CoA desaturase gene in Hu sheep. Factors affecting conjugated linoleic acid content in milk and meat. Changes in body composition with conjugated linoleic acid. A. , Vlaeminck, B. , Heys, S. , and Luedecke, L. , Nam, H. , Kaczmarczyk, M. , and Rossi, M. Uptake and utilization of trans octadecenoic acids in lactating dairy cows. , Rahman, M. , Kim, M. Conjugated linoleic acids. View abstract. , Pariset, L. Conjugated linoleic acid increases intracellular ROS synthesis and oxygenation of arachidonic acid in macrophages. , and Zhang, G. An assessment of c9,t11 linoleic acid intake in a small group of young Canadians. H. There can also be losses from drains, including nasogastric tubes. , and Bernal, C. , and Gong, D. , Ferlay, A. Differential incorporation of dietary conjugated linolenic and linoleic acids into milk lipids and liver phospholipids in lactating and suckling rats. , and Liu, J. C. , and Sebedio, J. We currently have no information for CONJUGATED LINOLEIC ACID Interactions CONJUGATED LINOLEIC ACID Dosing The following doses have been studied in scientific research: BY MOUTH For reducing body fat in obese patients, a dose of 1. , Gutowska, I. , Durand, D. , and Karges, K. , Babick, A. , and Mehrabi, Y. , Kemp, M. D. , and Gabel, M. , Bocca, C. , Bernal, C. , and Varela-Moreiras, G. , Andolfatto, C. M. Effects of conjugated linoleic acid (CLA) isomers on lipid levels and peroxisome proliferation in the hamster. , Rule, D. J. , Angelone, T. , Maillard, V. However, other research suggests that increased dietary intake of conjugated linoleic acid is not linked with a reduced risk of breast cancer. Production of free conjugated linoleic acid by Lactobacillus acidophilus and Lactobacillus casei of human intestinal origin. , Chardigny, J. 8 to 7 grams per day has been used. Cancers to suspect in patients with unexplained weight loss include gastrointestinal, prostate, hepatobilary ( hepatocellular carcinoma, pancreatic cancer ), ovarian, hematologic or lung malignancies. , Couture, P. , Petit, H. Dietary trans-10,cis-12 conjugated linoleic acid induces hyperinsulinemia and fatty liver in the mouse. E. , Devery, R. , Nuernberg, K. , Racca, A. and McIntosh, M. View abstract. , Opsomer, G. Wallace, R. , van Valenberg, H. Bernard, L. , Gilbert, C. , Fresno, J. S. L. , Park, Y. , and Rossi, R. L. , and Hedayati, M. Message Boards Connect with people like you, and get expert guidance on living a healthy life. I. Zhou, X. F. Dugan, M. , Schmidt, P. Uehara, H. , Hebert, N. Designed eggs containing conjugated linoleic acids and omega-3 polyunsaturated fatty acids. Dietary conjugated linoleic acid decreased cachexia, macrophage tumor necrosis factor-alpha production, and modifies splenocyte cytokines production. , Machalinski, B. , Or-Rashid, M. , and Griinari, J. J. A. , and Gilliland, S. Conjugated linoleic acid differentially modifies fatty acid composition in subcellular fractions of muscle and adipose tissue but not adiposity of postweaning pigs. , Scimeca, J. and Kreider, R. and Field, C. Torres, C. Schievano, E. , Takahashi, M. , Kuhlmann, D. Yurawecz, M. M. , Wiszniewska, B. Antioxidant enzyme defense responses of human MCF-7 and SW480 cancer cells to conjugated linoleic acid. , Firkins, J. , Adler, G. Dietary conjugated linoleic acid modulation of phorbol ester skin tumor promotion. , and Malan, Borel, I. , Palumbo, D. L. , Kalscheur, K. O. , Kang, J. Crisa, A. , Chiquette, J. , Dhiman, T. , Laskaridis, K. Benito, P. Churruca, I. W. View abstract. Andreoli, M. J. Other losses: Conditions such as burns can be associated with losses such as skin exudates. View abstract. Feeding wheat dried distillers grains with solubles improves beef trans and conjugated linoleic acid profiles. Quantitative gas chromatographic method for the analysis of cis-9, trans-11 and trans-10, cis-12 isomers of the conjugated linoleic acid in liver. Bergamo, P. , Rossi, R. View abstract. Effects of trans-10, cis-12 conjugated linoleic acid on ovine milk fat synthesis and cheese properties. Effects of essential oils on digestion, ruminal fermentation, rumen microbial populations, milk production, and milk composition in dairy cows fed alfalfa silage or corn silage. , Luongo, D. , Tachibana, H. , Doyle, P. Obesity. K. , Freese, R. Riserus U, Vessby B, Arner P, Zethelius B. , Dent, M. , Kelley, D. R. View abstract. Troegeler-Meynadier, A. R. Conjugated linoleic acid induces lipid peroxidation in men with abdominal obesity. Conjugated linoleic acid rapidly reduced body fat content in mice without affecting energy intake. Troglitazone but not conjugated linoleic acid reduces gene expression and activity of matrix-metalloproteinases-2 and -9 in PMA-differentiated THP-1 macrophages. , and Bernal, C. , Hippen, A. Donnelly, C. , Carraro, R. Research on the effects of conjugated linoleic acid for improving strength is conflicting. Patients who have uremia often have poor or absent appetite, vomiting and nausea. A. H. A. , and Fernandes, G. Conjugated Linoleic Acid (CLA) inhibits new vessel growth in the mammalian brain. Stachowska, E. , and Zou, S. View abstract. View abstract. Effect of Conjugated Linoleic Acid and Fatty Acid Positional Distribution on Physicochemical Properties of Structured Lipids. R. View abstract. , Oh, J. M. , Jeong, T. , Lewis, L. P. Yang, Y. , and Vessby, B. L. , and Fan, E. A. Factors influencing variation of fatty acid content in ovine milk. , Suzuki, R. , and Crooker, B. , Wang, Y. Conjugated linoleic acid and oxidative behaviour in cancer cells. M. Effects of C18 fatty acid isomers on DNA synthesis in hepatoma and breast cancer cells. , Shirasaka, N. G. , Bauchart, D. , and Inoue, N. Black, I. J. , Dentico, M. , and Sevi, A. E. A. , Rossi, R. , Latorre, A. and Omaye, S. , Rosi, F. , Ross, R. , Barlund, S. J. View abstract. , and Sugano, M. M. View abstract. , Vessby, B. Effect of conjugated linoleic acid isomers on insulin resistance and mRNA levels of genes regulating energy metabolism in high-fat-fed rats. trans-10,cis-12 Conjugated linoleic acid induces depolarization of mitochondrial membranes in HT-29 human colon cancer cells: a possible mechanism for induction of apoptosis. , Saal, D. , Wang, J. Choi, J. A. View abstract. Storey, A. A. Q. , Kushiro, M. , Lin, Y. D. , and Chen, Z. , and Song, J. , Napolitano, F. Schennink, A. , Pearce, E. M. , and Sidell, N. Cardiovascular disease, especially congestive heart failure, may cause unexplained weight loss. Infant plasma trans, n-6, and n-3 fatty acids and conjugated linoleic acids are related to maternal plasma fatty acids, length of gestation, and birth weight and length. Badr El-Din, N. , Falen, R. , Katinakis, P. AlZahal, O. , Bovenhuis, H. , and Reglero, G. , Pastorelli, G. Bocca, C. , Nickel, K. Surgery: Conjugated linoleic acid might cause extra bleeding during and after surgery. Dietary fatty acid sources affect conjugated linoleic acid concentrations in milk from lactating dairy cows. , Basu, S. Inhibition of stearoyl-CoA desaturase activity by the cis-9,trans-11 isomer and the trans-10,cis-12 isomer of conjugated linoleic acid in MDA-MB-231 and MCF-7 human breast cancer cells. View abstract. A. , Provo, J. , Ouellet, D. Study of Some Experimental Parameters in the Synthesis of Triacylglycerols with CLA Isomers and Structural Analysis. , Nader, G. View abstract. Hot topic: Fatty acid and conjugated linoleic acid (CLA) isomer composition of commercial CLA-fortified dairy products: evaluation after processing and storage. V. , Palmquist, D. , and McIntosh, M. , Shirai, N. , Paikin, J. , Marin, J. View abstract. Inhibitory effect of conjugated dienoic derivatives of linoleic acid and beta-carotene on the in vitro growth of human cancer cells. , Aeschlimann, G. A. , Johnson, M. U. References: Reza, J. , Zhang, J. View abstract. Biomolecular characterization of human glioblastoma cells in primary cultures: differentiating and antiangiogenic effects of natural and synthetic PPARgamma agonists. , Berdeaux, O. P. , Kawahara, S. , and Palmquist, D. N. , Kang, H. , and Ure, A. Devillard, E. Conjugated linoleic acid impairs endothelial function. S. C. Is conjugated linoleic acid (CLA) a protective factor in atherosclerosis. , Shultz, T. , Roche, H. P. , Taneli, F. Q. , and Fernandez-Quintela, A. , Ito, T. , and Ahn, J. , Smedman, A. Chen, J. Cesano Al, Visonneau S, Scimeca JA, et al. E. Q. , Tenti, S. , and Eder, K. Xu, H. , and Chilliard, Y. CLA Glutathione and Sodium DNA for Reducing Hair Loss. , Li, D. , Storkson, J. , Shingfield, K. View abstract. S. , Morgan, J. , Akoh, C. , Gresti, J. , Raff, M. and Gillis, M. The effect of dietary fiber level on milk fat concentration and fatty acid profile of cows fed diets containing low levels of polyunsaturated fatty acids. Desroches, S. View abstract. Effect of a mixture of conjugated linoleic acid isomers on growth performance and antibody production in broiler chicks. B. , and Yamada, K. , Jackson, M. , and Chlubek, D. View abstract. , and Mateo, J. W. , Hockings, J. S. , and Chilliard, Y. However, adding conjugated linoleic acid to milk might help decrease body fat in obese adults. , Fernandez-Quintela, A. 7 macrophage-derived foam cells. Basu, S. , Bird, C. , Cuesta-Alonso, E. , and Czuprynski, C. , Sebedio, J. , and Segato, S. View abstract. , Fredrikson, G. Bassaganya-Riera, J. Conjugated linoleic acid and the risk of breast cancer. , Ip, M. View abstract. , McKain, N. , Hendry, L. , and Kim, W. R. Chajes, V. , and Kramer, J. Prostaglandin E2 (PGE2) and thromboxane A2 (TXA2) synthesis is regulated by conjugated linoleic acids (CLA) in human macrophages. M. , Bovenhuis, H. Conjugated linoleic acid and atherosclerosis: no effect on molecular markers of cholesterol homeostasis in THP-1 macrophages. , Caroprese, M. Cao, Y. Caroprese, M. , Demizieux, L. , Zumalacarregui, J. , Kocsis, S. E. P. , Kwon, G. , Chen, J. , Driscoll, M. Treatment with dietary trans10cis12 conjugated linoleic acid causes isomer-specific insulin resistance in obese men with the metabolic syndrome. R. , Tachibana, H. A. However, other research shows that conjugated linoleic acid does not improve strength or body composition when used along with strength training. Influence of sodium glycocholate on production of conjugated linoleic acid by cells of Lactobacillus reuteri ATCC 55739. L. A. , and Xu, X. , Marino, R. , Zhao, R. , Rhys, R. , and Besnard, P. Effects of winter stocker growth rate and finishing system on: III. , Montalbano, A. View abstract. Duckett, S. , Yakubov, G. , Higuchi, T. , Harvatine, K. View abstract. , Sebedio, J. Chung, S. Y. E. L. , Kasai, M. D. , Ciechanowicz, A. C. , and Huang, Y. Bocca, C. Avoid use. , Zhang, X. F. Tsuyama, S. High dietary levels of a conjugated linoleic acid mixture alter hepatic glycerophospholipid class profile and cholesterol-carrying serum lipoproteins of rats. , Rastmanesh, R. Strength. , Dusterloh, K. , Chouinard, P. Safety of conjugated linoleic acid (CLA) in overweight or obese human volunteers. Effects of oil source and fish oil addition on ruminal biohydrogenation of fatty acids and conjugated linoleic acid formation in beef steers fed finishing diets. , Schulz, N. J. , Fitzgerald, D. R. , Gregoire, S. View abstract. , Plonne, M. Kamphuis MM, Lejeune MP, Saris WH, Westerterp-Plantenga MS. Akahoshi, A. , Dolegowska, B. Feeding soybean oil to dairy goats increases conjugated linoleic acid in milk. Taking conjugated linoleic acid by mouth daily might help decrease body fat in adults, but it does not seem to decrease body weight or body mass index (BMI) in most people. T. , and Bougnoux, P. View abstract. , Marzano, A. L. Y. , Li, D. , Sircar, D. , Kishino, S. , Nelson, G. Bernuy, B. , Hervas, G. Increasing the amount of fat in a conjugated linoleic acid-supplemented diet reduces lipodystrophy in mice. Determination of conjugated linoleic acid in human plasma by fast gas chromatography. View abstract. , and Larondelle, Y. J. , and Park, J. Z. , Yamasaki, M. A. , Sneddon, A. , Berglund, L. , Salimzadeh, A. , Kang, M. View abstract. R. , Jourdan, M. Yamasaki, M. , Mermillod, P. View abstract. Basu, S. , and Azain, M. , Bauman, D. , Vessby, B. , and Reglero, G. Conjugated linoleic acid and the control of cancer and obesity. While conjugated linoleic acid might help reduce body weight, some research shows that taking a particular form of conjugated linoleic acid (the trans-10,cis-12 isomer) might increase risk factors for type 2 diabetes and heart disease. E. Ribot, J. Conjugated linoleic acid (CLA), body fat, and apoptosis. Sinclair, L. , and Rossi, M. , and San Primitivo, F. , and Campos, H. Cancer, a very common and sometimes fatal cause of unexplained ( idiopathic ) weight loss. , and Chlubek, D. Y. Tyburczy, C. View abstract. , and Laforest, J. Yang, L. Yu, L. , Fitzgerald, G. T. View abstract. Devery, R. , Juarez, M. Aldai, N. , and Ku, Y. Dietary conjugated linoleic acids as free fatty acids and triacylglycerols similarly affect body composition and energy balance in mice. , Jiang, Z. , and Frutos, P. M. , Luciano, G. View abstract. , Geigerman, C. , and Sagredos, A. , and Shultz, T. A. P. , Colombatto, S. , Hontecillas, R. , Parkin, S. , Roy, B. , Early, R. , Albright, C. Zhang, G. R. Some early research suggests that higher intake of conjugated linoleic acid from foods, particularly cheese, seems to be linked with a lower risk of developing breast cancer. Trans-10,cis-12 CLA increases adipocyte lipolysis and alters lipid droplet-associated proteins: role of mTOR and ERK signaling. Andreoli, M. View abstract. Chilliard, Y. View abstract. , and Thuillier, P. Kinetics of fatty acid biohydrogenation in vitro. View abstract. Urquhart, P. , Luongo, D. Turpeinen, A.
Coakley, M. J. , Nuernberg, G. Effects of conjugated linoleic acid on linoleic and linolenic acid metabolism in man. Conjugated linoleic acid in humans: regulation of adiposity and insulin sensitivity. View abstract. H. , Mersmann, H. Stachowska, E. De La, Torre A. , Vanhatalo, A. Conjugated linoleic acid upregulates LDL receptor gene expression in HepG2 cells. Y. , Van Loan, M. W. , Niot, I. , Kim, H. , Saadat, N. , Mao, H. P. , and Maryam, C. , and Jianjun, X. T. Santillo, A. J. , Bober, J. B. Cunningham, D. H. , Jewell, C. , Tanemura, K. More evidence is needed to rate conjugated linoleic acid for these uses. , Jovinge, S. , Tachibana, H. , and Vessby, B. R. Advances in CLa and n-3 fatty acid research in human health. View abstract. , Gonzalez, M. J. , and Roehrig, K. , Fukuda, N. , Poirier, H. W. , and Weiler, H. , Wechsler, D. It might cause side effects such as stomach upset, diarrhea, nausea, and fatigue. , and Ide, T. , and van Arendonk, J. Scatliff, C. M. , Choi, O. L. View abstract. , Gibson, M. , Mansho, K. , and Li, D. Some research suggests that a diet high in conjugated linoleic acid might be linked with a lower risk of cancer of the colon and rectum in women. Enter the shape, color, or imprint of your prescription or OTC drug. Taking conjugated linoleic acid does not improve pre-meal or post-meal blood sugar or insulin levels in people with type 2 diabetes. , and Clapham, W. Insulin resistance-associated cardiovascular disease: potential benefits of conjugated linoleic acid. However, doses greater than 3. , Bang, M. View abstract. A. , Shin, J. Milk quality as affected by grazing time of day in Mediterranean goats. Z. C. , Destaillats, F. Effect of PUFA on embryo cryoresistance, gene expression and AMPKalpha phosphorylation in IVF-derived bovine embryos. , Fitzgerald, G. , Chew, B. M. , Bartolini, G. Conjugated linoleic acids: are they beneficial or detrimental to health. , Yamasaki, M. , Shahram, F. , Lanza, M. , Javadi, M. N. H. Ritzenthaler, K. Stop using it at least 2 weeks before a scheduled surgery. , Miyazaki, T. Effect of dietary conjugated linoleic acids on the distribution of fatty acids in serum lipoprotein fractions and different tissues of growing pigs. , Schingoethe, D. Miner JL, Cederberg CA, Nielsen MK, et al. , Macarulla, M. L. View abstract. , Miyanaga, F. , James, P. , and Fitzpatrick-Wong, S. , and Gallagher, P. , Ross, P. G. , Watanabe, K. , Mele, M. Yamasaki, M. , Jakubowska, K. High-fat dairy food and conjugated linoleic acid intakes in relation to colorectal cancer incidence in the Swedish Mammography Cohort. S. Demaree, S. The effect of dietary inclusion of olive tree leaves and grape marc on the content of conjugated linoleic acid and vaccenic acid in the milk of dairy sheep and goats. J. , and Simon, V. , Miyamoto, S. , and Ezaki, O. M. View abstract. B. Estimation of conjugated linoleic acid intake by written dietary assessment methodologies underestimates actual intake evaluated by food duplicate methodology. , Paillard, D. , Contarini, G. Conjugated linoleic acids modulate UVR-induced IL-8 and PGE2 in human skin cells: potential of CLA isomers in nutritional photoprotection. , Yin, D. Effects of CLA at different dietary fat levels on the nutritional status of rats during protein repletion. Smit, L. , Tahbaz, F. , Flemetakis, E. , and Hayes, K. , Harrison, L. R. , Fritsche, J. , Kris-Etherton, P. Salva, B. F. K. , Xu, H. , Djazayeri, A. , Yuan, J. J. , and Moioli, B. Chronic but not acute treatment with conjugated linoleic acid (CLA) isomers (trans-10, cis-12 CLA and cis-9, trans-11 CLA) affects lipid metabolism in Caco-2 cells. Metabolic syndrome: There are concerns that taking conjugated linoleic acid might increase the risk of getting diabetes if you have metabolic syndrome. Furthermore, some research suggests that increased intake of conjugated linoleic acid might be linked with an increased risk of breast cancer. Mougios V, Matsakas A, Petridou A, et al. S. , McIntosh, F. , Dijkstra, J. View abstract. E. , Liu, J. , Scollan, N. , and Chlubek, D. , Rogers, J. , Sugano, M. L. B. M. K. Eating restrictions may also be imposed as part of treatment or investigations. , Monereo, S. Y. , and Song, J. M. H. Tsiplakou, E. View abstract. Conjugated linoleic acid attenuates cyclooxygenase-2 transcriptional activity via an anti-AP-1 mechanism in MCF-7 breast cancer cells. Santillo, A. , Macarulla, M. , Turu, C. Effect of conjugated linoleic acids, vitamin E and their combination on the clinical outcome of Iranian adults with active rheumatoid arthritis. and Lea, M. Tarnopolsky, M. Ringseis, R. , Gonzalo, C. , Tange, T. Tanmahasamut, P. Modulation of body fat and serum leptin levels by dietary conjugated linoleic acid in Sprague-Dawley rats fed various fat-level diets. Bauman, D. , Guillaume, D. A. , Czuprynska, K. E. T. , Aldai, N. Q. View abstract. , Park, Y. F. M. , Choy, J. , Muscio, A. N. , Senorans, F. , Carriedo, J. R. , Miyashita, K. R. Conjugated linoleic acid can prevent tumor necrosis factor gene expression by inhibiting nuclear factor binding activity in peripheral blood mononuclear cells from weaned pigs challenged with lipopolysaccharide. , and Stanton, C. , De Santis, E. O. , Brown, J. , and Turkmen, M. , Shingfield, K. , and Osoro, K. S. , Saebo, P. Corino, C. N. , Sandberg, M. M. , Glasser, F. , and Li, D. A. , Yeung, S. T. M. View abstract. , and Chlubek, D. , and Simon, V. , Dziedziejko, V. Zhou, X. , and Dauchy, R. , and Caja, G. , Marti, A. Yuan, G. , Ogawa, J. View abstract. Tappia, P. , Barbosa, E. Conjugated linoleic acid supplementation for 1 y reduces body fat mass in healthy overweight humans. , Eastman, A. , and Oh, S. Changes to metabolic demands can be caused by illness, surgery and organ dysfunction. Effects of conjugated linoleic acid supplementation on body composition and leptin concentration in post-menopausal women. View abstract. Yasui, Y. Degrace, P. , and Wu, Y. T. , and Smith, S. , and Vessby, B. , Hirao, A. E. N. , and Miglietta, A. , Kaczmarczyk, M. , Richard, D. Poor appetite can be a direct symptom of an illness, or an illness could make eating painful or induce nausea. , Ross, R. , Albanell, E. AlZahal, O. E. , and Vessby, B. Research on the effects of conjugated linoleic acid for preventing breast cancer is conflicting. Broughton, K. J. E. Atkinson, R. L. , Pasman, W. Effect of abomasal infusions of a mixture of octadecenoic acids on milk fat synthesis in lactating cows. View abstract. Y. , and Ma, D. View abstract. , Baskiewicz-Masiuk, M. R. G. , Nagao, K. F. C. , and Bruun, J. , Saal, D. Conjugated linoleic acid promotes human adipocyte insulin resistance through NFkappaB-dependent cytokine production. View abstract. Inability to eat can result from: diminished consciousness or confusion, or physical problems affecting the arm or hands, swallowing or chewing. How to Treat Childhood Skin Problems Pregnancy App The big day is coming. Yanagita, T. K. A. , Rac, M. , Hostens, M. , Tepper, S. View abstract. , Gabriel, L. Chen, X. View abstract. Sugano, M. , Ross, R. , and Stanton, C. , Hosseinpanah, F. Subbaiah, P. Conjugated linoleic acid metabolism. Dietary conjugated linoleic acid lowers plasma cholesterol during cholesterol supplementation, but accentuates the atherogenic lipid profile during the acute phase response in hamsters. W. C. Stability analysis of zinc oxide-nanoencapsulated conjugated linoleic acid and gamma-linolenic acid. A. , Safranow, K. , and Gilliland, S. , Chalecki, A. Clement, L. Dietary conjugated linoleic acids decrease leptin in porcine adipose tissue. , Kalscheur, K. , Leblanc, N. , Miller, P. , Zhao, G. , Hopkins, R. J. D. , Willett, W. , Bozzo, F. View abstract. V. D. Conjugated linoleic acid might help reduce body fat deposits and improve immune function. , Banni, S. , and Yamada, K. , Vazquez, L. J. J. Src may be involved in the anti-cancer effect of conjugated linoleic acid. Opposite effects of linoleic acid and conjugated linoleic acid on human prostatic cancer in SCID mice. , and Vessby, B. Adding conjugated linoleic acid to fatty foods does not seem to promote weight loss. B. B. Sher, J. , Kelley, D. T. Bouattour, M. View abstract. , Bober, J. , and Gruffat, D. Dehkordi, S. E. , Kramer, J. Q. E. , Aro, A. , Ender, K. Toxicological evaluation of dietary conjugated linoleic acid in male Fischer 344 rats. K. , Perfield, J. Ringseis, R. View abstract. P. View abstract. F. , Mele, M. Butterfat fatty acids differentially regulate growth and differentiation in Jurkat T-cells. Dietary conjugated linoleic acid increases PPAR gamma gene expression in adipose tissue of obese rat, and improves insulin resistance. Blankson H, Stakkestad JA, Fagertun H, et al. View abstract. , Fitzgerald, G. , Sugano, M. L. G. , Sinclair, A. Stachowska, E. , Figueira, A. , Issa-Zacharia, A. View abstract. An average diet supplies 15-174 mg of conjugated linoleic acid daily. , and Bittante, G. , Hausman, D. Weiler, H. L. , Mouriot, J. A. , Pariza, M. D. Campbell, B. , Pinault, M. , and Pariza, M. , Cuesta, E. , Packnejad, M. M. Dietary supplementation with conjugated linoleic acid increased its concentration in human peripheral blood mononuclear cells, but did not alter their function. M. Y. , Bailat, A. , Matte, J. View abstract. , Zheng, C. , Berdeaux, O. Effect of supplementation with conjugated linoleic acid on human serum lipids and body fat. , and Keim, N. , Gibney, M. M. View abstract. , Mutanen, M. C. Bozzo, F. , Sevi, A. , Machalinski, B. Schiavon, S. Characterization and stability analysis of zinc oxide nanoencapsulated conjugated linoleic Acid. View abstract. C. View abstract. , Salehipour, M. , and Dannenberger, D. , and Zimmerman, D. , Salminen, I. Proliferative responses of normal human mammary and MCF-7 breast cancer cells to linoleic acid, conjugated linoleic acid and eicosanoid synthesis inhibitors in culture. , Pasini, G. , Parra, M. Chuang, L. , Shiyan, Q. H. L. M. Smedman, A. Yang, M. M. , and Devillard, E. , Colombatto, S. Y. , and Zhang, G. Smit, L. , Fredrikson, G. Inflammation and conjugated linoleic acid: mechanisms of action and implications for human health. K. , and Miglietta, A. View abstract. E. , Meurens, M. View abstract. , Olszewska, M. , Lessard, M. View abstract. K. Azain, M. , and McBride, B. , and Monserrat, L. Stachowska, E. , Muller, A. View abstract. 4 grams per day do not seem to offer any additional benefit. Colonic anti-inflammatory mechanisms of conjugated linoleic acid. F. , Wen, G. View abstract. , Maurano, F. J. , Shah, A. Sheep and goats differences in CLA and fatty acids milk fat content in relation with mRNA stearoyl-CoA desaturase and lipogenic genes expression in their mammary gland. , Oh, M. J. , Jovinge, S. Cho, H. H. , Tse, I. , Bober, J. Roman-Nunez, M. , Dasgupta, N. Conjugated linoleic acid reduces body fat mass in overweight and obese humans. , Barbano, D. Unsaturated fatty acids bind Myc-Max transcription factor and inhibit Myc-Max-DNA complex formation. , Sehat, N. Barrett, E. , and Yang, M. Serini, S. , Straarup, E. V. , Doosti, M. , Lai, C. , and Chouinard, P. , Ogborn, M. , Yamada, K. , Corneau, L. , Pujos-Guillot, E. Bernard, L. Y. , Beynen, A. Effects of dietary conjugated linoleic acid at high-fat levels on triacylglycerol regulation in mice. V. , Horton, M. View abstract. , Moreno, T. , and Fievez, V. , Merendino, N. S. , and Oh, S. , Gibb, D. Conjugated linoleic acid--mediated apoptosis in Jurkat T cells involves the production of reactive oxygen species. , Wright, S. , McGuire, M. , Lue, B. L. , Debiton, E. , Bee, G. , Papadomichelakis, G. , Cetinoz, F. , and Enjalbert, F. , Liu, J. Milk fatty acids in dairy cows fed whole crude linseed, extruded linseed, or linseed oil, and their relationship with methane output. , and Leaf, A. , Barthomeuf, C. , and Basu, S. , and Furuse, M. Regulation of fat synthesis by conjugated linoleic acid: lactation and the ruminant model. W. , Goto, Y. C. View abstract. A new conjugated linoleic acid isomer, 7 trans, 9 cis-octadecadienoic acid, in cow milk, cheese, beef and human milk and adipose tissue. , Mojarrad, M. Our pill identification tool will display pictures that you can compare to your pill. Zhao, L. F. Effect of dietary conjugated linoleic acid supplementation in sows on performance and immunoglobulin concentration in piglets. L. , Tanaka, Y. , Casals, R. , Szumilowicz, H. , Pariza, M. , and McBride, B. , Vitari, F. Ribeiro, C. View abstract. Zhong, W. , Nam, J. , Schingoethe, D. Dietary conjugated linoleic acid modifies the brain endocannabinoid system in mice. , Rogers, J. , Martin, R. F. , Viana, A. G. , Kelley, D. , Santoli, D. Intentional weight loss is commonly referred to as slimming. Albright, C. Download Living Healthy Featured Content Improve Your Concentration These Foods and Drinks Can Help Allergy App Fight allergies with daily forecasts, local alerts, and personalized tips. , Iglesias, J. A review of fatty acid profiles and antioxidant content in grass-fed and grain-fed beef. , and Huhtanen, P. , and Mohede, I. , Mocchiutti, N. , and Romagnolo, D. , Ye, Y. View abstract. L. , Lea-Currie, Y. , and Negishi, S. , Quinto, M. R. A comparative study of the effects of erabu sea snake (Laticauda semifasciata) lipids, green tea extract and conjugated linoleic acid on the swimming endurance of mice. , Neel, J. , Bellafiore, M. , and Rossi, M. Dietary supplementation with conjugated linoleic acid does not alter the resistance of mice to Listeria monocytogenes infection. , Dupont, J. Bondia-Pons, I. , Guerre-Millo, M. J. , Gu, Z. Effects of dietary conjugated linoleic acid in advanced experimental polycystic kidney disease. , Kramer, J. M. , and Masso-Welch, P. , Herradon, P. Bergamo, P. , Dobson, G. F. Yu-Poth, S. It is not known whether taking conjugated linoleic acid supplements provides the same benefit. , Weber, W. Di Giancamillo, A. , Cook, M. Taking conjugated linoleic acid along with ramipril seems to reduce blood pressure more than ramipril alone in people with uncontrolled high blood pressure. Chung, S. , and Beitz, D. D. Conjugated linoleic acid suppresses the growth of human breast adenocarcinoma cells in SCID mice. R. View abstract. , Noguchi, M. R. Chujo, H. , Petit, M. , and Steinhart, H. C. Shultz, T. Effect of conjugated linoleic acid supplementation after weight loss on appetite and food intake in overweight subjects. Bonet, S. , Van Straalen, W. , Visker, M. E. Stachowska, E. , Lidan, Z. , and Culver, B. Berven, G. , and Bauman, D. P. K. , Muscio, A. , Fitzgerald, G. Silveira, M. , Corino, C. View abstract. , Juarez, M. , Yang, L. , Elia, C. , and Ilich, J. , Chardigny, J. View abstract. , Arenas, R. E. , Catillo, G. Effect of lactation stage and energy status on milk fat composition of Holstein-Friesian cows. M. View abstract. , Eder, K. P. , Kasaoka, S. Zabala, A. , Gu, Z. , Perreau, C. T. View abstract. L. P. B. , and Ide, T. View abstract. , Naderi, N. , Yin, J. , Jindong, Y. Safflower oil consumption does not increase plasma conjugated linoleic acid concentrations in humans. , van Ommen, B. F. Watkins, B. View abstract. View abstract. Short-term intake of conjugated linoleic acid inhibits lipoprotein lipase and glucose metabolism but does not enhance lipolysis in mouse adipose tissue. , Martinelli, M. Silberberg, Y. Physiological response to lipid peroxidation in ischemia and reperfusion during carotid endarterectomy. M. Sauer, L. Get Started Drug News Vitamin B12 May Not Help Some Seniors Do Supplements Give Athletes an Edge. and Cook, M. Conjugated linoleic acid increased C-reactive protein in human subjects. Degner, S. Sasikala-Appukuttan, A. Duckett, S. View abstract. L. P. Brownbill, R. , and Yamada, K. Dairy products and beef are the major dietary sources. , Basu, S. Degner, S. View abstract. , McArdle, F. , and Roche, H. D. D. , Baskiewicz, M. Intentional weight loss is the loss of total body mass as a result of efforts to improve fitness and health, or to change appearance through slimming. , and Shimizu, S. , and Sevi, A. , Ni, J. W. , Cesano, A. Maternal dietary Alpine butter intake affects human milk: fatty acids and conjugated linoleic acid isomers. , Molto-Puigmarti, C. , Marchitelli, C. Conjugated linoleic acid and disease prevention: a review of current knowledge. , Duncan, S. Milk fatty acid unsaturation: genetic parameters and effects of stearoyl-CoA desaturase (SCD1) and acyl CoA: diacylglycerol acyltransferase 1 (DGAT1). , Giguere, A. L. Bassaganya-Riera, J. New Schizophrenia Drug Approved FDA: New, Stronger Warning for NSAIDs New Drug Approved for Heart Failure Mobile Drug Information App Drug, supplement, and vitamin information on the go. View abstract. View abstract. , Ryan, C. , Portillo, M. So, M. Zlatanos, S. , and Seaman, W. Al Darwich, A. F. Inhibition of phospholipase A(2) activity by conjugated linoleic acids in human macrophages. , Saebo, A. , Dong, B. , Tachibana, H. Takahashi, K. , Gonzalez, L. , Akiba, Y. Bernardini, D. , and Stanton, C. , Lock, A. H. , and Hals, O. , Martin, C. , Martinez, A. F. , Marchesini, G. , Kelleher, D. , Okuyama, H. E. P. View abstract. , Fontenot, J. S. , Williams, S. , Park, Y. , Ney, J. , and McIntosh, M. View abstract. Lack of food can result from: poverty, difficulty in shopping or cooking, and poor quality meals. Andreoli, M. , Hussey, S. A. , and Adlof, R. Taking Medications During Pregnancy Pill Identifier Having trouble identifying your pills. Riserus, U. , Schleser, S. H. J. , Gutowska, I. , and Ntambi, J. , Bozzo, F. , Gliatta, G. , Luque, A. , Seaman, W. , Maurano, F. Zambell, K. , Kasai, M. , Causey, J. , Yang, L. M. Isomer-specific effects of conjugated linoleic acid on lipid peroxidation in humans: regulation by alpha-tocopherol and cyclo-oxygenase-2 inhibitor. , Hontecillas-Magarzo, R. Bhattacharya, A. , Tsuji, Y. Vu, P. , Yokozeki, K. , and Miglietta, A. J. , Berthiaume, R. M. , Abbott, A. Rosberg-Cody, E. , and Pelling, A. , and Villegas, J. Shingfield, K. Conjugated linoleic acid suppresses colon carcinogenesis in azoxymethane-pretreated rats with long-term feeding of diet containing beef tallow. , Greenwood, S. , Quintanar, R. Influence of conjugated linoleic acid isomers on the metastasis of colon cancer cells in vitro and in vivo. , Recseg, K. trans-fatty acid isomers in adipose tissue have divergent associations with adiposity in humans. , and Stanton, C. Roman, J. , and Clouet, P. , and Swain, R. , McIntosh, F. H. Conjugated linoleic acid ameliorates viral infectivity in a pig model of virally induced immunosuppression. Ando, A. View abstract. Belury, M. , Staels, B. Differences between human subjects in the composition of the faecal bacterial community and faecal metabolism of linoleic acid. , Guo, Z. , and Liu, S. , Jung, M. A. CLA differently regulates adipogenesis in stromal vascular cells from porcine subcutaneous adipose and skeletal muscle. Boeckaert, C. L. Conjugated linoleic acid reduces hepatic steatosis and restores liver triacylglycerol secretion and the fatty acid profile during protein repletion in rats. J. , Halvorsen, Y. Devillard, E. Fatty acid composition of milk from multiparous Holstein cows treated with bovine somatotropin and fed n-3 fatty acids in early lactation. Conjugated linoleic acids for body fat mass reduction. , Toivonen, V. Zhang, H. , and Cashman, K. , and Kritchevsky, D. Toke, N. , Mishima, H. B. Xiao, Y. Thatcher, W. J. , Tagliapietra, F. , Wortelboer, H. , Nou, S. Bernuy, B. , and van Arendonk, J. Vasta, V. , Douglas, M. , Ikemoto, S. Effects of conjugated linoleic acid on insulin sensitivity and diabetes markers in type 2 diabetic patients. A. Conjugated linoleic acid biosynthesis by human-derived Bifidobacterium species. , and Larondelle, Y. , and Wahle, K. , Bray, T. T. K. , Jikuya, H. About one-third of unintentional weight loss cases are secondary to malignancy. Conjugated linoleic acid inhibits Caco-2 cell growth via ERK-MAPK signaling pathway. , Thomas, N. , and Li, E. Metabolic effects of conjugated linoleic acid in humans: the Swedish experience. , and Jacques, H. , Basu, S. , and Guignot, F. , Rahman, M. , Sugimoto, K. , Meurens, M. Heterologous expression of linoleic acid isomerase from Propionibacterium acnes and anti-proliferative activity of recombinant trans-10, cis-12 conjugated linoleic acid. Y. Riserus, U. , and Calviello, G. , Delisle, J. Supplementation with conjugated linoleic acid causes isomer-dependent oxidative stress and elevated C-reactive protein: a potential link to fatty acid-induced insulin resistance. , Eshragian, M. , and Frenneaux, M. K. , Kasai, M. M. D. , and Priolo, A. Zeng, Z. , Huang, Y. , and Tebar, J. Conjugated linoleic acid content in breast adipose tissue is not associated with the relative risk of breast cancer in a population of French patients. , Hernandez, M. View abstract. Taking conjugated linoleic acid does not seem to prevent weight gain in previously obese people who lost some weight. , Mignolet, E. , Kalloniati, C. H. , Such, X. , and Belton, O. Effects of cis-9,trans-11 conjugated linoleic acid supplementation on insulin sensitivity, lipid peroxidation, and proinflammatory markers in obese men. , Iglesias-Gutierrez, E. , Ogino, Y. Chung, S. Upregulation of tumor necrosis factor-alpha expression by trans10-cis12 conjugated linoleic acid enhances phagocytosis of RAW macrophages via a peroxisome proliferator-activated receptor gamma-dependent pathway. Dietary conjugated linoleic acid reciprocally modifies ketogenesis and lipid secretion by the rat liver. , and Chen, Z. Tsuboyama-Kasaoka, N. , and Kreuzer, M. M. View abstract. , and Doreau, M. Darestani, A. , Riserus, U. , and Feng, S. P. , Aizezi, B. J. , Toivonen, V. , and Domeneghini, C. , Baylin, A. , Basu, S. M. A. There is not enough evidence to know if long-term use is safe. , Oh, J. , and Yamada, K. , Dziedziejko, V. Conjugated linoleic acid isomers reduce cholesterol accumulation in acetylated LDL-induced mouse RAW264. , and Gou, K. Conjugated linoleic acid blocks estrogen signaling in human breast cancer cells. , Lund, P. , St Pierre, N. Flaxseed supplementation improves fatty acid profile of cow milk. , Gerardi, G. Zulet, M. desBordes, C. , Aroutiounova, N. P. The feeding value of corn distillers solubles for lactating dairy cows. , Fitzpatrick, S. , Papillier, P. , Nordgren, M. View abstract. , Vasquez, L. View abstract. , Miller, C. J. S. D. R. , Storkson, J. Improved glucose tolerance, skeletal muscle insulin action, and UCP-2 gene expression. R. , Leuenberger, H. , and Sieber, R. A. Dhiman, T. B. , Krief, S. , Marino, R. View abstract. , Rouel, J. J. , Beppu, F. , Dziedziejko, V. , Bozzo, F. M. Stability Profile of Fatty Acids in Yak ( Bos grunniens) Kidney Fat During the Initial Stages of Autoxidation. , Ahvenjarvi, S. K. Identification of lactic acid bacterial strains with high conjugated linoleic acid-producing ability from natural sauerkraut fermentations. Di, Felice, V, Macaluso, F. Alonso, L. Yuan, G. C. Effect of dietary fat sources on systemic and intrauterine synthesis of prostaglandins during early pregnancy in gilts. , Scerra, M. A. Tholstrup, T. H. , Kim, S. Conjugated linoleic acid induces mast cell recruitment during mouse mammary gland stromal remodeling. , and Aukema, H. , Brown, J. , Li, F. , Loreau, O. F. Effects of a dairy product (pecorino cheese) naturally rich in cis-9, trans-11 conjugated linoleic acid on lipid, inflammatory and haemorheological variables: a dietary intervention study. Conjugated linoleic acid isomers and their conjugated derivatives inhibit growth of human cancer cell lines. , and Priolo, A. , Murao, K. The effect of conjugated linoleic acid on plasma lipoproteins and tissue fatty acid composition in humans. A. , and McIntosh, M. H. , Miyazaki, H. Conjugated linoleic acid and its effects on animal products and health in single-stomached animals. Benito, P. M. C. F. , Eisenberg, B. , Wright, S. L. View abstract. , Marchlewicz, M. , and Du, M. , Franco, D. Taylor, J. K. , Dugan, M. , Shinohara, K. , and Martinez, J. Carriquiry, M. , Steinhart, H. , Sakuradani, E. , Bosley, J. View abstract. , Nicot, M. K. , and Eder, K. , Torrelo, G. Lack of effect of dietary conjugated linoleic acids naturally incorporated into butter on the lipid profile and body composition of overweight and obese men. , Leonard, A. S. Dietary omega-3 fatty acids differentially influence ova release and ovarian cyclooxygenase-1 and cyclooxygenase-2 expression in rats. Corino, C. M. , Bye, A. , Osorio, M. H. , Heck, J. M. Conjugated linoleic acid isomers inhibit platelet-derived growth factor-induced NF-kappaB transactivation and collagen formation in human vascular smooth muscle cells. View abstract. S. Transfer of absorbed cis-9, trans-11 conjugated linoleic acid into milk is biologically more efficient than endogenous synthesis from absorbed vaccenic acid in lactating cows. , Sarrafnejad, A. Song, H. View abstract. Tischendorf, F. , and Poppe, L. Conjugated linoleic acid reduces body fat in healthy exercising humans. , Lee, H. Effect of subacute ruminal acidosis on milk fat concentration, yield and fatty acid profile of dairy cows receiving soybean oil. , and Sugano, M. C. , Makkar, H. , Bhattacharya, A. Steck, S. , Hajri, T. View abstract. Avoid use. P. The effects of yogurt with isomer enriched conjugated linoleic acid on insulin resistance in obese adolescents. M. , Signorelli, F. , Colakoglu, M. Preferential incorporation of trans, trans-conjugated linoleic acid isomers into the liver of suckling rats. Chartrand, R. H. , Mukerji, P. J. View abstract. Soel, S. View abstract. , Kemp, M. Physical activity and milk intake with conjugated linoleic acid (CLA) in healthy people with excess weight. A. Sisk, M. View abstract. , Navarro, V. , Adler, G. B. Amaru, D. , Kohno, H. A. , Iwata, T. Daley, C. C. , and Baumgard, L. cis-9, trans-11 CLA derived endogenously from trans-11 18:1 reduces cancer risk in rats. View abstract. , and Staples, C. , Nagy, V. van Erk, M. , Shin, J. Vasta, V. Effect of fish oil and sunflower oil on rumen fermentation characteristics and fatty acid composition of digesta in ewes fed a high concentrate diet. Cook, M. Shingfield, K. Brown, J. An Efficient Methodology for the Preparation of Alkoxyglycerols Rich in Conjugated Linoleic Acid and Eicosapentaenoic Acid. Concentration-dependent antioxidant activities of conjugated linoleic acid and alpha-tocopherol in corn oil. M. Schmid, A. C. Conjugated linoleic acid decreases mcf-7 human breast cancer cell growth and insulin-like growth factor-1 receptor levels. Production and Application of Novel Sterol Esterases from Aspergillus Strains by Solid State Fermentation. Veaute, C. R. L. , Morgan, J. Influence of pasture on fatty acid profile of goat milk. , Dahlen, C. Coakley, M. , Quinto, M. , and Shimizu, E. Stangl, G. , and Bernal, C. Diabetes: There are concerns that taking conjugated linoleic acid can worsen diabetes. Research suggests that taking conjugated linoleic acid does not prevent or reduce symptoms of the common cold. , Hippen, A. J. B. Sakono, M. , Bonfigli, A. Conjugated linoleic acid attenuates the production and gene expression of proinflammatory cytokines in weaned pigs challenged with lipopolysaccharide. But there is not enough evidence to know if conjugated linoleic acid is safe to use in medicinal mounts during pregnancy and breast-feeding.
